PixelJunk Eden
Developer: Q-Games Limited
Platform: PlayStation 3 (free demo, paid full version)
Nominations: Excellence in Visual Art, Excellence in Audio, Technical Excellence
Description: Swing around on alient plant life, smashing things as you go along, as well as growing new plants.

Osmos
Developer: Hemisphere Games
Platform: Windows (free demo available)
Nominations: Seumas McNally Grand Prize, Excellence in Design, Technical Excellence
Description: Bounce around a petri dish, eating the weak and fleeing the strong. The catch? Moving costs you size, making you weaker.

The Maw
Developer: Twisted Pixel Games
Nomination: Technical Excellence
Platform: XBLA
Website
Description: Help feed a sweetly smiling bundle of teeth until he’s big enough to help you escape . . . and eat the world. Try not to think about the collateral damage. Twisted Pixel has officially apologized for unleashing the Maw, which will lead to the eventual consumption of the universe.

IncrediBots
Developer: Grubby Games
Nomination: Technical Excellence
Platform: Web Browser (Flash)
Website
Description: An engine for building and animating two dimensional robots, teaching them to do tricks, and making movies.

Cortex Command
Developer: Data Realms
Nomination: Technical Excellence
Platform: Windows, Mac OSX
Website
Description: You play a disembodied head with remote access to control zombie bodies and cool robots to do your bidding. Like all right-minded people, you use this power to look for gold and shoot people who get in your way.